(Aminoalkyl)diphenylphosphine sulfides: synthesis and application as building blocks in the design of multidentate ligands for cytotoxic Pd(<scp>ii</scp>) complexes-Reference-Cited by-同舟云学术

(Aminoalkyl)diphenylphosphine sulfides: synthesis and application as building blocks in the design of multidentate ligands for cytotoxic Pd(ii) complexes

Published:2023 Issue:41 Volume:21 Page:8379-8392
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Konovalov Aleksandr V.¹²,Churusova Svetlana G.¹,Aleksanyan Diana V.¹³^ORCID,Rybalkina Ekaterina Yu.⁴,Aksenova Svetlana A.¹⁵,Peregudov Alexander S.¹,Klemenkova Zinaida S.¹,Kozlov Vladimir A.¹

Affiliation:

1. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, str. 1, Moscow, 119334, Russia

2. Russian University of Chemical Technology, Miusskaya pl. 9, Moscow, 125047, Russia

3. Scientific Laboratory “Advanced Composite Materials and Technologies”, Plekhanov Russian University of Economics, Stremyannyi per. 36, Moscow, 117997, Russia

4. N. N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation, Kashirskoe shosse 23, Moscow, 115478, Russia

5. Moscow Institute of Physics and Technology (National Research University), Institutskiy per. 9, Dolgoprudny, Moscow Region, 141700, Russia

Abstract

The facile approaches to α-(aminoalkyl)diphenylphosphine sulfides are devised based on simple transformations of readily available precursors. The compounds obtained are used as building blocks for the production of cytotoxic Pd(ii) complexes.

Funder

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01309J

Reference23 articles.

1. From rocks to bioactive compounds: a journey through the global P(v) organophosphorus industry and its sustainability

2. Remarkable Potential of the α-Aminophosphonate/Phosphinate Structural Motif in Medicinal Chemistry

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4. Experimental and computational insights into the direct cyclopalladation of different unsymmetrical, yet closely related pincer ligands with thione sulfur donors

5. Dinucleating ligands based on functionalized oxalamides: Lability of Re(I) coordination with the phosphorus pendant arms