Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry-Reference-Cited by-同舟云学术

Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry

Published:2020 Issue:2 Volume:20 Page:215-225
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Baudy Andreas R.¹²³^ORCID,Otieno Monicah A.⁴⁵³,Hewitt Philip⁶⁷⁸,Gan Jinping⁹¹⁰³^ORCID,Roth Adrian¹¹¹²¹³,Keller Douglas¹⁴³^ORCID,Sura Radhakrishna¹⁵¹⁶³,Van Vleet Terry R.¹⁵¹⁶³,Proctor William R.¹⁷¹⁸³

Affiliation:

1. Merck & Co., Inc.

2. Kenilworth

3. USA

4. Janssen Pharmaceutical Research and Development

5. Spring House

6. Merck KGaA

7. Darmstadt

8. Germany

9. Bristol-Myers Squibb

10. New York City

11. Roche Innovation Centre

12. Basel

13. Switzerland

14. Sanofi, Bridgewater

15. AbbVie, Inc.

16. Chicago

17. Genentech, Inc.

18. South San Francisco

Abstract

This pharmaceutical industry guidance based on a 3-staged benchmarking strategy aims to help MPS developers and end users identify what could be the most valuable models for safety risk assessment, as well as provide an overview of contexts of use.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/C9LC00768G

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