Affiliation:
1. Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India
Abstract
The first Ir-catalyzed enantioselective β-allenylation of 2-hydroxynaphthoquinones is developed. The β-allenylic lawsone derivatives displayed remarkable potency against Gram-positive MRSA strain and low toxicity against mammalian cell lines.
Funder
Science and Engineering Research Board
Indian Institute of Science
Ministry of Education, India
Department of Science and Technology, Ministry of Science and Technology
Publisher
Royal Society of Chemistry (RSC)