Importance of two-dimensional cation clusters induced by protein folding in intrinsic intracellular membrane permeability-Reference-Cited by-同舟云学术

Importance of two-dimensional cation clusters induced by protein folding in intrinsic intracellular membrane permeability

Published:2022 Issue:8 Volume:3 Page:1076-1084
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Negi Shigeru¹^ORCID,Hamori Mami¹,Kawahara-Nakagawa Yuka²,Imanishi Miki³^ORCID,Kurehara Miku¹,Kitada Chieri¹,Kawahito Yuri¹,Kishi Kanae⁴,Manabe Takayuki⁵,Kawamura Nobuyuki⁶^ORCID,Kitagishi Hiroaki⁷^ORCID,Mashimo Masato¹,Shibata Nobuhito¹,Sugiura Yukio¹

Affiliation:

1. Faculty of Pharmaceutical Science, Doshisha Women's University, Koudo, Kyotanabe, Kyoto 610-0395, Japan

2. Graduate School of Life Science, University of Hyogo, 3-2-1 Kouto, Kamigori-cho, Ako-gun, Hyogo, 678-1297, Japan

3. Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan

4. Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima, 734-8553, Japan

5. Clinical Research Support Center, Asahikawa Medical University Hospital, 2-1-1-1 Midorigaokahigashi, Asahikawa 078-8510, Japan

6. Education Center for Pharmacy, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Akiha-ku, Niigata City, Niigata 956-8603, Japan

7. Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Kyoto 610-0321, Japan

Abstract

Two-dimensional cation clusters formed on the surface of proteins play an important role in their intracellular translocation.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CB/D2CB00098A

Reference64 articles.

1. Progress in biopharmaceutical development

2. Discovery and development of biopharmaceuticals: current issues

3. Protein transduction domain delivery of therapeutic macromolecules

4. Introduction to current and future protein therapeutics: A protein engineering perspective

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