Ultra-thin and ultra-porous nanofiber networks as a basement-membrane mimic-Reference-Cited by-同舟云学术

Ultra-thin and ultra-porous nanofiber networks as a basement-membrane mimic

Published:2023 Issue:20 Volume:23 Page:4565-4578
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Graybill Philip M.¹^ORCID,Jacobs Edward J.¹^ORCID,Jana Aniket²,Agashe Atharva²,Nain Amrinder S.²,Davalos Rafael V.¹^ORCID

Affiliation:

1. Bioelectromechanical Systems Lab, Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, VA, USA

2. Spinneret-Based Tunable Engineering Parameters (STEP) Lab, Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA, USA

Abstract

A high porosity (88%) and ultrathin (<3 μm) fibrous basement membrane mimic using (A) suspended nanofiber networks for a (B) brain endothelial–pericyte co-culture model. (C) Our approach achieved low cell membrane and nuclei separations.

Funder

Foundation for the National Institutes of Health

National Science Foundation

Institute for Critical Technology and Applied Science

Virginia Polytechnic Institute and State University

National Center for Advancing Translational Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00304C

Reference78 articles.

1. Modeling Barrier Tissues In Vitro: Methods, Achievements, and Challenges

2. Reconstituting Organ-Level Lung Functions on a Chip

3. Lung-on-a-chip: the future of respiratory disease models and pharmacological studies

4. Gut-on-a-chip: Current progress and future opportunities

5. Microfluidic Skin‐on‐a‐Chip Models: Toward Biomimetic Artificial Skin

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