An efficient green protocol for the preparation of acetoacetamides and application of the methodology to a one-pot synthesis of Biginelli dihydropyrimidines. Expansion of dihydropyrimidine topological chemical space
Author:
Affiliation:
1. Instituto de Química
2. Universidade Federal do Rio de Janeiro
3. Centro de Tecnologia
4. 21949-909 Rio de Janeiro
5. Brazil
Abstract
A one pot synthesis of Biginelli dihydropyrimidines. The novel use of the amino acids allows topological diversification of the chemical space.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA14355A
Reference133 articles.
1. Utilisation of 1,3‐Dicarbonyl Derivatives in Multicomponent Reactions
2. Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
3. Asymmetric domino reactions. Part A: Reactions based on the use of chiral auxiliaries
4. Chemo-differentiating ABB′ multicomponent reactions. Privileged building blocks
5. Multicomponent Reactions of Carbonyl Compounds and Derivatives of Cyanoacetic Acid: Synthesis of Carbo- and Heterocycles
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Synthetic approach to 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides based on common β-keto amide precursors;Beilstein Journal of Organic Chemistry;2023-11-23
2. Synthesis of six-membered Si-containing heterocycles based on acetoacetanilide;Journal of Organometallic Chemistry;2023-09
3. An Efficient and Sustainable Synthesis of the Antimalarial Drug Tafenoquine;ACS Sustainable Chemistry & Engineering;2022-12-07
4. Synthesis, molecular docking, and in silico ADME studies of dihydropyrimidine derivatives using tetrabutylphosphonium methanesulphonate ionic liquid as a catalyst under solvent-free conditions;Canadian Journal of Chemistry;2022-06
5. Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches;Viruses;2021-04-27
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3