A practical approach to asymmetric synthesis of dolastatin 10-Reference-Cited by-同舟云学术

A practical approach to asymmetric synthesis of dolastatin 10

Published:2017 Issue:29 Volume:15 Page:6119-6131
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhou Wen¹²³⁴,Nie Xiao-Di¹²³⁴,Zhang Yu⁵⁶⁷⁴,Si Chang-Mei¹²³⁴,Zhou Zhu¹²³⁴,Sun Xun¹²³⁴,Wei Bang-Guo¹²³⁴^ORCID

Affiliation:

1. School of Pharmacy and Institutes of Biomedical Sciences

2. Fudan University

3. Shanghai

4. China

5. College of Energy

6. Xiangan campus of Xiamen University

7. Xiamen

Abstract

Dolastatin 10 has been effectively synthesized through SmI₂-induced cross-coupling for Dap, asymmetric addition for Doe and an alternative route to Val-Dil.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01395G

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