Protecting group-directed annulations of tetra-substituted oxindole olefins and sulfur ylides: regio- and chemoselective synthesis of cyclopropane- and dihydrofuran-fused spirooxindoles-Reference-Cited by-同舟云学术

Protecting group-directed annulations of tetra-substituted oxindole olefins and sulfur ylides: regio- and chemoselective synthesis of cyclopropane- and dihydrofuran-fused spirooxindoles

Published:2019 Issue:22 Volume:9 Page:12255-12264
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kang Jing-Wen¹²³⁴,Li Xiang¹²³⁴,Chen Fei-Yu¹²³⁴,Luo Yuan¹²³⁴,Zhang Shu-Cang¹²³⁴,Kang Bin¹²³⁴,Peng Cheng¹²³⁴^ORCID,Tian Xu⁵⁶⁷⁸⁴,Han Bo¹²³⁴^ORCID

Affiliation:

1. State Key Laboratory Breeding Base of Systematic Research Development and Utilization of Chinese Medicine Resources School of Pharmacy

2. Chengdu University of Traditional Chinese Medicine

3. Chengdu 611137

4. P. R. China

5. Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease

6. School of Pharmaceutical Sciences & the Fifth Affiliated Hospital

7. Guangzhou Medical University

8. Guangzhou 511436

Abstract

Protecting group-controlled regio- and chemoselective synthesis of cyclopropane- and dihydrofuran-fused spirooxindoles containing vicinal quaternary carbon centers.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Sichuan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA02192B

Reference83 articles.

1. Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents

2. Simple indole alkaloids and those with a non-rearranged monoterpenoid unit