Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles-Reference-Cited by-同舟云学术

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Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles

Published:2019 Issue:2 Volume:7 Page:596-606
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Li Yamin¹²³⁴^ORCID,Bolinger Justin¹²³⁴,Yu Yingjie¹²³⁴,Glass Zachary¹²³⁴,Shi Nicola¹²³⁴^ORCID,Yang Liu¹²³⁴,Wang Ming⁵⁶⁷⁸⁹,Xu Qiaobing¹²³⁴^ORCID

Affiliation:

1. Department of Biomedical Engineering

2. Tufts University

3. Medford

4. USA

5. Beijing National Laboratory for Molecular Sciences

6. Key Laboratory of Analytical Chemistry for Living Biosystems

7. Institute of Chemistry

8. Chinese Academy of Sciences

9. Beijing

Abstract

A combinatorial library of cationic lipidoids were used as nanocarriers for intracellular delivery of the CRISPR/Cas9 ribonucleoprotein complex.

Funder

National Science Foundation

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/BM/C8BM00637G

Reference62 articles.

1. Multiplex Genome Engineering Using CRISPR/Cas Systems

2. RNA-Guided Human Genome Engineering via Cas9

3. CRISPR/Cas, the Immune System of Bacteria and Archaea

4. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

5. CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery

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3. Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies;Biotechnology Advances;2024-05

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