Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center-Reference-Cited by-同舟云学术

Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center

Published:2019 Issue:3 Volume:9 Page:1487-1490
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chen Bo¹²³⁴⁵,Chu Wen-Dao¹²³⁴⁵^ORCID,Liu Quan-Zhong¹²³⁴⁵

Affiliation:

1. Chemical Synthesis and Pollution Control

2. Key Laboratory of Sichuan Province

3. College of Chemistry and Chemical Engineering

4. China West Normal University

5. Nanchong 637002

Abstract

A Cu(ii)/bisoxazoline ligand-promotes the formal [4 + 1] cycloaddition of diazo esters with azoalkenes formed in situ. This provides a protocol for construction of dihydropyrazoles containing a quaternary center with good to excellent yields.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C8RA08909D

Reference56 articles.

1. Asymmetric creation of quaternary carbon centers

2. Asymmetric Catalysis Special Feature Part I: Catalytic asymmetric synthesis of all-carbon quaternary stereocenters

3. J.Christoffers and A.Baro , Quaternary Stereocenters-Challenges and Solutions for Organic Synthesis , Wiley-VCH , Weinheim , 2005