Enhancing oncolytic virus efficiency with methionine and N-(3-aminoprolil)methacrylamide modified acrylamide cationic block polymer

Author:

Chen Gong1,Yuan Yuan234,Li Ying23,He Qianyuan1,Qin Zizhen5,Hu Han1,Gao Congcong1,Xu Zushun1ORCID,Xu Qi1,Gao Qinglei23,Li Fei23

Affiliation:

1. Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, School of Materials Science and Engineering, Hubei University, Wuhan 430062, China

2. Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430034, China

3. National Clinical Research Centre for Obstetrics and Gynecology, Cancer Biology Research Centre (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430034, China

4. Cancer Center, Renmin Hospital of Wuhan University, Wuhan 430060, China

5. Key laboratory of Biorheological Science and Technology, Ministry of Educations, Collage of Bioengineering, Chongqing University, Chongqing, 40044, China

Abstract

Schematic illustration of the preparation of NAD/Ad complex and the working mechanism for cancer therapy.

Funder

Data Center of Management Science, National Natural Science Foundation of China - Peking University

Publisher

Royal Society of Chemistry (RSC)

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