Cisplatin resistance reversal in lung cancer by tumor acidity-activable vesicular nanoreactors via tumor oxidative stress amplification-Reference-Cited by-同舟云学术

Cisplatin resistance reversal in lung cancer by tumor acidity-activable vesicular nanoreactors via tumor oxidative stress amplification

Published:2021 Issue:13 Volume:9 Page:3055-3067
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Mukerabigwi Jean Felix¹²³⁴⁵^ORCID,Han Yu¹²³⁶⁷,Lu Nannan⁸⁹³,Ke Wendong¹²³,Wang Yuheng¹²³,Zhou Qinghao¹²³,Mohammed Fathelrahman¹²³,Ibrahim Alhadi¹²³,Zheng Bin⁶⁷¹⁰,Ge Zhishen¹²³⁸⁹^ORCID

Affiliation:

1. CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China

2. Hefei 230026

3. China

4. Department of Applied Chemistry, College of Science and Technology, University of Rwanda

5. Kigali

6. School of Chemistry and Chemical Engineering, Hefei Normal University

7. Hefei

8. Department of Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China

9. Hefei 230001

10. People's Republic of China

Abstract

A vesicular therapeutic nanoreactor coloading glucose oxidase and cisplatin is engineered to effectively inhibit cisplatin-resistant tumor growth through the amplification of intracellular oxidative stress and activation of pro-apoptotic pathways.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D0TB02876B

Reference61 articles.

1. Cisplatin in the modern era: The backbone of first-line chemotherapy for non-small cell lung cancer

2. The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs