A review on the assembly of multi-substituted pyridines <i>via</i> Co-catalyzed [2 + 2 + 2] cycloaddition with nitriles-Reference-Cited by-同舟云学术

A review on the assembly of multi-substituted pyridines via Co-catalyzed [2 + 2 + 2] cycloaddition with nitriles

Published:2022 Issue:37 Volume:20 Page:7391-7404
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Cen Kaili¹,Usman Muhammad²^ORCID,Shen Wangzhen¹,Liu Meijing³,Yang Rong¹,Cai Jinhui¹^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China

2. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

3. College of Pharmaceutical Science, University of South China, Hengyang 421001, Hunan, China

Abstract

This review mainly focuses on the recent advances in Co-catalyzed [2 + 2 + 2] cycloaddition reaction of alkynes with nitriles to access multi-substituted pyridines. Meanwhile, brief mechanistic insights are also discussed to explain the observed regioselectivity.

Funder

University of South China

Natural Science Foundation of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01344D

Reference102 articles.

1. Synthesis of (+)-Complanadine A, an Inducer of Neurotrophic Factor Excretion

2. Comprehensive Heterocyclic Chemistry II , ed. C. W. Bird , Pergamon , Oxford , 1996