Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein-Reference-Cited by-同舟云学术

Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein

Published:2016 Issue:1 Volume:12 Page:59-66
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Chang Chung-ke¹²³⁴,Jeyachandran Sivakamavalli⁵⁶⁷⁴,Hu Nien-Jen⁸⁶⁷⁴,Liu Chia-Ling⁵⁶⁷⁴,Lin Shing-Yen⁵⁶⁷⁴,Wang Yong-Sheng⁵⁶⁷⁴,Chang Yu-Ming⁹²¹⁰⁴,Hou Ming-Hon⁵⁶⁷⁴⁸

Affiliation:

1. Institute of Biomedical Science

2. Academia Sinica

3. Nangang

4. Taiwan

5. Institute of Genomics and Bioinformatics and Institute of Life Sciences

6. National Chung Hsing University

7. Taichung 40254

8. Institute of Biochemistry

9. Institute of Biological Chemistry

10. Taipei 11529

Abstract

Nucleocapsid protein (NP), an essential RNA-binding viral protein in human coronavirus (CoV)-infected cells, is an antiviral target for drug discovery.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MB/C5MB00582E

Reference34 articles.

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