Characterization of a coumarin C-/O-prenyltransferase and a quinolone C-prenyltransferase from Murraya exotica-Reference-Cited by-同舟云学术

Characterization of a coumarin C-/O-prenyltransferase and a quinolone C-prenyltransferase from Murraya exotica

Published:2022 Issue:28 Volume:20 Page:5535-5542
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Li Na¹²,Liu Xiao¹^ORCID,Zhang Mingliang¹²,Zhang Zekun¹²,Zhang Beibei¹²,Wang Xiaohui¹,Wang Juan¹,Tu Pengfei¹³,Jiang Yong³^ORCID,Shi She-po¹^ORCID

Affiliation:

1. Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100102, China

2. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China

3. State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China

Abstract

Two new prenyltransferases were characterized from M. exotica. MePT1 catalyses the simultaneous formation of C- and O-prenylated products from coumarins, MePT2 regio-specifically generates 3-C-dimethylallylated products from quinolone alkaloids.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01054B

Reference40 articles.

1. The effect of developmental and environmental factors on secondary metabolites in medicinal plants

2. Prenyltransferases as key enzymes in primary and secondary metabolism

3. Plant Aromatic Prenyltransferases: Tools for Microbial Cell Factories

4. Parallel evolution of UbiA superfamily proteins into aromatic O-prenyltransferases in plants

5. Antileishmanial activity of prenylated coumarins isolated from Ferulago angulata and Prangos asperula

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of O-Methyltransferases Potentially Contributing to the Structural Diversity of 2-(2-Phenylethyl)chromones in Agarwood;Journal of Agricultural and Food Chemistry;2024-06-03

2. A comprehensive review of the botany, phytochemistry, pharmacology, and toxicology of Murrayae Folium et Cacumen;Frontiers in Pharmacology;2024-03-28

3. Substrate-Dependent Alteration in the C- and O-Prenylation Specificities of Cannabis Prenyltransferase;Biological and Pharmaceutical Bulletin;2024-02-17

4. Terpenoids from Penicillium chrysogenum MT-40, an endophytic fungus isolated from Huperzia serrata;Organic Chemistry Frontiers;2023