Synthesis and evaluation of radiolabeled porphyrin derivatives for cancer diagnoses and their nonradioactive counterparts for photodynamic therapy-Reference-Cited by-同舟云学术

Synthesis and evaluation of radiolabeled porphyrin derivatives for cancer diagnoses and their nonradioactive counterparts for photodynamic therapy

Published:2022 Issue:12 Volume:13 Page:1565-1574
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Ramzi Nur Izni¹,Mishiro Kenji²,Munekane Masayuki¹,Fuchigami Takeshi¹,Hu Xiaojun³,Jastrząb Renata⁴,Kitamura Yoji⁵,Kinuya Seigo⁶,Ogawa Kazuma¹²^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan

2. Institute for Frontier Science Initiative, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan

3. Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China

4. Faculty of Chemistry, Adam Mickiewicz University of Poznan, Uniwersytetu Poznanskiego 8, Poznan 61-614, Poland

5. Research Center for Experimental Modeling of Human Disease, Kanazawa University, Takara-machi 13-1, Kanazawa, Ishikawa 920-8640, Japan

6. Department of Nuclear Medicine, Kanazawa University Hospital, Kanazawa University, Takara-machi 13-1, Kanazawa, Ishikawa 920-8641, Japan

Abstract

The prepared radiolabeled porphyrin derivatives showed high accumulation in tumor tissues and good phototoxicities indicating their potential for cancer theranostics.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/MD/D2MD00234E

Reference49 articles.

1. Porphyrin as Diagnostic and Therapeutic Agent

2. Clinical Practice of Photodynamic Therapy Using Talaporfin Sodium for Esophageal Cancer

3. Photodynamic Therapy Using Talaporfin Sodium for Local Failure after Chemoradiotherapy or Radiotherapy for Esophageal Cancer: A Single Center Experience

4. Photodynamic Therapy for Malignant Brain Tumors

5. The role of porphyrin chemistry in tumor imaging and photodynamic therapy

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