Donor acceptor fluorophores: synthesis, optical properties, TD-DFT and cytotoxicity studies

Author:

Essam Zahraa M.12345,Ozmen Guliz Ersoy12345,Setiawan Dani12345,Hamid Riri Rizkianty62345,Abd El-Aal Reda M.1789,Aneja Ritu62345,Hamelberg Donald12345,Henary Maged12345ORCID

Affiliation:

1. Department of Chemistry

2. Petit Science Center

3. Georgia State University

4. Atlanta

5. USA

6. Department of Biology

7. Suez University

8. Suez

9. Egypt

Abstract

We report a series of NIR D–A fluorophores with a cyanoacrylic acid acceptor and various donor units. The cytotoxicity of selected fluorophores against triple negative breast cancer cell lines showed stronger activity than that of anticancer agent docetaxel.

Funder

Egyptian Cultural and Educational Bureau

Georgia State University

Atlanta Clinical and Translational Science Institute

Georgia Research Alliance

National Science Foundation

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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