Rational design of poly(peptide-ester) block copolymers for enzyme-specific surface resorption-Reference-Cited by-同舟云学术

Rational design of poly(peptide-ester) block copolymers for enzyme-specific surface resorption

Published:2023 Issue:28 Volume:11 Page:6621-6633
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Fung Stephanie L.¹^ORCID,Cohen Jarrod P.²^ORCID,Pashuck E. Thomas²³^ORCID,Miles Catherine E.²^ORCID,Freeman Joseph W.¹^ORCID,Kohn Joachim²^ORCID

Affiliation:

1. Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA

2. Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA

3. Department of Bioengineering, Lehigh University, Bethlehem, PA, 18018, USA

Abstract

We report the development of a peptide-polyester block copolymer where protease-mediated resorption is tuned through the chemistry of the polymer backbone and protease specificity is imparted through incorporation of specific peptide sequences.

Funder

National Institute of Biomedical Imaging and Bioengineering

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D3TB00265A

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