Enantioselective synthesis of sterically hindered α-allyl–α-aryl oxindoles via palladium-catalysed decarboxylative asymmetric allylic alkylation-Reference-Cited by-同舟云学术

Enantioselective synthesis of sterically hindered α-allyl–α-aryl oxindoles via palladium-catalysed decarboxylative asymmetric allylic alkylation

Published:2017 Issue:38 Volume:15 Page:8166-8178
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Jackson Mark¹²³⁴⁵^ORCID,O'Broin Calvin Quince¹²³⁴⁵^ORCID,Müller-Bunz Helge¹²³⁴⁵,Guiry Patrick J.¹²³⁴⁵^ORCID

Affiliation:

1. Centre for Synthesis and Chemical Biology

2. School of Chemistry

3. University College Dublin

4. Dublin 4

5. Ireland

Abstract

The highly enantioselective synthesis of sterically hindered α-allyl–α-aryl oxindoles possessing an all-carbon quaternary stereocenter at the oxindole 3-position has been developed.

Funder

Irish Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02161E

Reference55 articles.

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3. Maremycins C and D, New Diketopiperazines, and Maremycins E and F, Novel Polycyclicspiro-Indole Metabolites Isolated fromStreptomycessp.

4. Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I

5. Oxindole Derivatives as Orally Active Potent Growth Hormone Secretagogues

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