In the pursuit of novel therapeutic agents: synthesis, anticancer evaluation, and physicochemical insights of novel pyrimidine-based 2-aminobenzothiazole derivatives-Reference-Cited by-同舟云学术

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In the pursuit of novel therapeutic agents: synthesis, anticancer evaluation, and physicochemical insights of novel pyrimidine-based 2-aminobenzothiazole derivatives

Published:2024 Issue:23 Volume:14 Page:16332-16348
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ismail Toka I.¹,El-Khazragy Nashwa²³^ORCID,Azzam Rasha A.¹^ORCID

Affiliation:

1. Chemistry Department, Faculty of Science, Helwan University, Cairo, 11795, Egypt

2. Department of Clinical Pathology-Hematology, Ain Shams Medical Research Institute (MASRI), Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt

3. Department of Genetics and Molecular Biology, Egypt Center for Research and Regenerative Medicine (ECRRM), Cairo 11599, Egypt

Abstract

2-Aminobenzothiazole derivatives, have attracted interest for their versatility in generating novel anticancer agents. This study explores the synthesis, and anticancer evaluation of new pyrimidine-based 2-aminobenzothiazole derivatives.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA01874E

Reference43 articles.

1. Riluzole, Neuroprotection and Amyotrophic Lateral Sclerosis

2. Riluzole: A neuroprotective drug with potential as a novel anti‑cancer agent (Review)

3. Anthelmintic efficacy of tinidazole against the progression of Toxocara canis larvae to the brain in mice

4. The immunomodulatory action of frentizole, a novel immunosuppressive agent

5. 2-Aminobenzothiazoles in anticancer drug design and discovery

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