Alkali-amide-catalyzed divergent sp2 and sp3 C–H bonds alkylation of alkylthiophenes with alkenes-Reference-Cited by-同舟云学术

Alkali-amide-catalyzed divergent sp2 and sp3 C–H bonds alkylation of alkylthiophenes with alkenes

Published:2021 Issue:15 Volume:8 Page:4171-4176
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Luo Yan-Long¹²³⁴⁵,Du Hui-Zhen¹²³⁴⁵,Guan Bing-Tao⁶⁷⁸⁵^ORCID

Affiliation:

1. State Key Laboratory and Institute of Elemento-Organic Chemistry

2. College of Chemistry

3. Nankai University

4. Tianjin 300071

5. China

6. Department of Chemistry

7. Fudan University

8. Shanghai 200438

Abstract

Divergent sp² and sp³ C–H bonds alkylation of alkylthiophenes was achieved selectively with LDA and KHMDS catalysts, providing not only atom-economical synthesis approaches but also some insights in the different behaviours of the alkali amides.

Funder

Fudan University

Natural Science Foundation of Tianjin City

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00627D

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