Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET): 11- and 15-hydroxy 8,9-EETs
Author:
Affiliation:
1. Departments of Entomology and Nematology and UC Davis Comprehensive Cancer Center
2. University of California Davis
3. Davis
4. USA
5. UC Davis Genome Center-Metabolomics
Abstract
COX metabolites of 8,9-EET, previously observed as potent mitogenic lipid mediators, were synthesized for the first time by using two synthetic approaches.
Funder
National Institute of Environmental Health Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00789B
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1. Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate
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