Mitochondrial topoisomerase 1 targeted anticancer therapy using irinotecan encapsulated mesoporous MIL-101(Fe) synthesized <i>via</i> a vapour assisted method-Reference-Cited by-同舟云学术

Mitochondrial topoisomerase 1 targeted anticancer therapy using irinotecan encapsulated mesoporous MIL-101(Fe) synthesized via a vapour assisted method

Published:2024 Issue:7 Volume:53 Page:3010-3019
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Ghosh Anirban¹,Ghosh Arijit²,Bhattacharyya Arpan²^ORCID,Mitra Riddhi¹^ORCID,Das Benu Brata²^ORCID,Bhaumik Asim¹^ORCID

Affiliation:

1. School of Materials Sciences, Indian Association for the Cultivation of Science, 2A & 2B Raja S. C. Mullick Road, Jadavpur, Kolkata 700 032, India

2. Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata–700 032, India

Abstract

MOF-mediated selective delivery of irinotecan into the mitochondria to trap mitochondrial Top1-covalent complexes for anticancer chemotherapy.

Funder

Department of Atomic Energy, Government of India

Council of Scientific and Industrial Research, India

Department of Science & Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D3DT03654E

Reference48 articles.

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4. A new strongly paramagnetic cerium-containing microporous MOF for CO2 fixation under ambient conditions

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