A FRET-based fluorescent Zn2+sensor: 3D ratiometric imaging, flow cytometric tracking and cisplatin-induced Zn2+fluctuation monitoring
Author:
Affiliation:
1. State Key Laboratory of Coordination Chemistry
2. Coordination Chemistry Institute
3. School of Chemistry and Chemical Engineering
4. Nanjing University
5. Nanjing 210023
Abstract
A Zn2+sensor exhibiting 3D ratiometric imaging and flow cytometric ability was constructed based on the FRET mechanism, and cisplatin-induced endogenous labile Zn2+fluctuations were monitored in real time.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Jiangsu Province
Nanjing University
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC03037F
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