Reconstituting donor T cells increase their biomass following hematopoietic stem cell transplantation

Author:

Leslie Kevin A.1234ORCID,Rasheed Mahmood52346,Sabo Roy T.6234,Roberts Catherine C.52346,Toor Amir A.52346,Reed Jason12347

Affiliation:

1. Department of Physics

2. Virginia Commonwealth University

3. Richmond

4. USA

5. Department of Internal Medicine

6. Department of Biostatistics

7. Massey Cancer Center

Abstract

In this study, we used a rapid, highly-sensitive, single-cell biomass measurement method, Live Cell Interferometry (LCI), to measure biomass in populations of CD3 + T cells isolated from hematopoietic stem cell transplant (SCT) patients at various times pre- and post-transplant (days 0–100).

Funder

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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