A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis-Reference-Cited by-同舟云学术

A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis

Published:2015 Issue:116 Volume:5 Page:95545-95550
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Micale N.¹²³⁴,Piperno A.⁵²⁶⁴,Mahfoudh N.⁷⁸⁹¹⁰¹¹,Schurigt U.¹²¹³¹⁴¹⁵,Schultheis M.¹²¹³¹⁴¹⁵,Mineo P. G.⁵¹⁶¹⁷⁴^ORCID,Schirmeister T.¹⁸¹⁹²⁰¹⁵,Scala A.⁵²⁶⁴,Grassi G.⁵²⁶⁴

Affiliation:

1. Department of Drug Sciences and Health Products

2. University of Messina

3. 98168 Messina

4. Italy

5. Department of Chemical Sciences

6. 98166 Messina

7. Department of Medicinal and Organic Chemistry

8. University of Granada

9. Faculty of Pharmacy

10. 18071 Granada

11. Spain

12. Institute for Molecular Infection Biology

13. University of Würzburg

14. Würzburg 97074

15. Germany

16. University of Catania

17. 95125 Catania

18. Institute of Pharmacy and Biochemistry

19. University of Mainz

20. D-55128 Mainz

Abstract

A new HA–Pent bioconjugate was synthetized and proposed as drug targeting delivery system for the treatment of leishmaniasis, exploiting the specific biological recognition of HA by the macrophage.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA18019H

Reference35 articles.

1. Leishmaniasis Worldwide and Global Estimates of Its Incidence

2. Kala Azar – letaler Verlauf einer viszeralen Leishmaniose

3. Antileishmanial drug discovery: comprehensive review of the last 10 years

4. Structures, Targets and Recent Approaches in Anti-Leishmanial Drug Discovery and Development

5. Amphotericin B-loaded poly(ethylene glycol)–poly(lactide) micelles: Preparation, freeze-drying, andin vitro release

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