Palladium-catalysed ligand-free reductive Heck cycloisomerisation of 1,6-en-α-chloro-enamides-Reference-Cited by-同舟云学术

Palladium-catalysed ligand-free reductive Heck cycloisomerisation of 1,6-en-α-chloro-enamides

Published:2019 Issue:26 Volume:55 Page:3733-3736
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Hou Yangyang¹²³⁴⁵,Ma Jing¹²³⁴⁵,Yang Hongyi¹²³⁴⁵,Anderson Edward A.⁶⁷⁸⁹^ORCID,Whiting Andy¹⁰¹¹¹²⁹^ORCID,Wu Na¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources

2. School of Chemistry and Pharmaceutical Science

3. Guangxi Normal University

4. Gulin

5. China

6. Chemistry Research Laboratory

7. Oxford University

8. Oxford

9. UK

10. Department of Chemistry

11. Durham University

12. Durham DH1 3LE

Abstract

The first example of an intramolecular hydroarylation of 1,6-en-α-chloro-enamides was achieved by a palladium-catalysed ligand-free reductive Heck cycloisomerisation with no competing Heck-cyclised by-product.

Funder

National Natural Science Foundation of China

Newton Fund

Guangxi Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC00537D

Reference38 articles.

1. The Mechanism of the Phosphine-Free Palladium-Catalyzed Hydroarylation of Alkynes

2. Palladium(0)/NHC-Catalyzed Reductive Heck Reaction of Enones: A Detailed Mechanistic Study

3. Geometry-Constrained Iminopyridyl Palladium-Catalyzed Hydroarylation of Alkynes to Prepare Tri-substituted Alkenes Using Alcohol as Reductant

4. Palladium-Catalyzed Asymmetric Reductive Heck Reaction of Aryl Halides

5. Palladium-Catalyzed Enantioselective Reductive Heck Reactions: Convenient Access to 3,3-Disubstituted 2,3-Dihydrobenzofuran

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metal‐Free Oxyacetoxylation of Arylynamines and Ynamides To Construct α‐Acetoxyl Amides;European Journal of Organic Chemistry;2023-07-26

2. α-Haloenamides: Synthesis and Subsequent Transformations;Synthesis;2022-08-09

3. Preparation of 1-Benzyl-7-methylene-1,5,6,7-tetrahydro-4H-benzo[d]imidazol-4-one;Organic Syntheses;2021

4. Synthesis of Sulfonamide-Based Ynamides and Ynamines in Water;The Journal of Organic Chemistry;2020-12-23

5. Synthesis of 3-Selenylindoles through Organoselenium-Promoted Selenocyclization of 2-Vinylaniline;The Journal of Organic Chemistry;2020-11-05