The corona of protein–gold nanoparticle systems: the role of ionic strength

Author:

Cantarutti Cristina1ORCID,Hunashal Yamanappa12,La Rosa Carmelo3ORCID,Condorelli Marcello3ORCID,Giorgetti Sofia4,Bellotti Vittorio45,Fogolari Federico67ORCID,Esposito Gennaro27ORCID

Affiliation:

1. DAME, Università di Udine, 33100 Udine, Italy

2. Science Division, New York University Abu Dhabi, Abu Dhabi, UAE

3. Dip. Scienze Chimiche, Università di Catania, 95125 Catania, Italy

4. Dipartimento di Medicina Molecolare, Università di Pavia, 27100 Pavia, Italy

5. Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London NW3 2PF, UK

6. DMIF, Università di Udine, 33100 Udine, Italy

7. INBB, Viale Medaglie d’Oro 305, 00136 Roma, Italy

Abstract

By simply changing the ionic strength of the medium, it is possible to switch from a labile and transient nature of the protein–gold nanoparticle adduct, to a layer of proteins having a long residence time on the nanoparticle surface.

Funder

New York University Abu Dhabi

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

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