Microfluidic electrical impedance assessment of red blood cell-mediated microvascular occlusion

Author:

Man Yuncheng1234ORCID,Maji Debnath5234ORCID,An Ran1234,Ahuja Sanjay P.67234,Little Jane A.6891011,Suster Michael A.5234,Mohseni Pedram523412,Gurkan Umut A.123412ORCID

Affiliation:

1. Mechanical and Aerospace Engineering Department

2. Case Western Reserve University

3. Cleveland

4. USA

5. Electrical, Computer, and Systems Engineering Department

6. Division of Hematology and Oncology

7. Rainbow Babies and Children's Hospital

8. UNC Blood Research Center

9. Department of Medicine

10. University of North Carolina at Chapel Hill

11. Chapel Hill

12. Department of Biomedical Engineering

Abstract

Microfluidic Impedance Red Cell Assay (MIRCA) is integrated with capillary network-inspired micropillar arrays and electrical impedance sensing electrodes to enable standardized assessment of red blood cell-mediated microvascular occlusion.

Funder

National Heart, Lung, and Blood Institute

National Science Foundation

American Heart Association

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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