Aberrant zinc binding to immature conformers of metal-free copper–zinc superoxide dismutase triggers amorphous aggregation-Reference-Cited by-同舟云学术

Aberrant zinc binding to immature conformers of metal-free copper–zinc superoxide dismutase triggers amorphous aggregation

Author:

Leal Sónia S.¹²³^ORCID,Cristóvão Joana S.¹²³^ORCID,Biesemeier Antje⁴⁵⁶,Cardoso Isabel⁷⁸⁹^ORCID,Gomes Cláudio M.¹²³

Affiliation:

1. Instituto Tecnologia Química e Biológica

2. Universidade Nova de Lisboa

3. Oeiras, Portugal

4. Center for Ophthalmology and Core Facility for Electron Microscopy at the University Hospital

5. University of Tubingen

6. Germany

7. Modulation in Neurodegenerative Disorders (MiND group)

8. Instituto de Biologia Molecular e Celular

9. Porto, Portugal

Abstract

Aberrant zinc coordination to immature conformers broadens the population of SOD1 misfolded species at early aggregation stages.

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

Reference90 articles.

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