Retracted Article: A multifunctional self-dissociative polyethyleneimine derivative coating polymer for enhancing the gene transfection efficiency of DNA/polyethyleneimine polyplexes in vitro and in vivo
Author:
Affiliation:
1. State Key Laboratory of Natural Medicines
2. Department of Pharmaceutics
3. China Pharmaceutical University
4. Nanjing 210009
5. China
Abstract
A novel coating polymer LPHF is developed for the first time to elevate the transfection efficiency of DP binary polyplexes in vitro and in vivo.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2015/PY/C4PY01135J
Reference38 articles.
1. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
2. Polyethyleneimine-grafted hyperbranched conjugated polyelectrolytes: synthesis and imaging of gene delivery
3. Developing a chitosan supported imidazole Schiff-base for high-efficiency gene delivery
4. The strategy to improve gene transfection efficiency and biocompatibility of hyperbranched PAMAM with the cooperation of PEGylated hyperbranched PAMAM
5. Toxicity of cationic lipids and cationic polymers in gene delivery
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