Investigation of etravirine uptake and distribution in single aortic endothelial cells in vitro using Raman imaging

Author:

Orleanska Jagoda123ORCID,Wiecek Wiktoria1,Majzner Katarzyna1ORCID

Affiliation:

1. Jagiellonian University in Krakow, Faculty of Chemistry, Department of Chemical Physics, Gronostajowa 2 St, 30-387 Krakow, Poland

2. Jagiellonian University in Krakow, Doctoral School of Exact and Natural Sciences, Prof. St. Lojasiewicza St 11, 30-348 Krakow, Poland

3. Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics (JCET), Bobrzynskiego St 14, 30-348 Krakow, Poland

Abstract

Tracking ETV through Raman images reveals its concentration and incubation time-dependent uptake in HAEC cells, which leads to subsequent biochemical changes in endothelial cells.

Funder

Narodowe Centrum Nauki

Uniwersytet Jagielloński w Krakowie

Publisher

Royal Society of Chemistry (RSC)

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