Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia
Author:
Affiliation:
1. Fachbereich Chemie
2. Philipps-Universität Marburg
3. 35043 Marburg
4. Germany
5. Department of Pathology
6. University of Michigan
7. Ann Arbor
8. USA
9. LOEWE Zentrum für Synthetische Mikrobiologie SynMikro
Abstract
Shine light on epigenetics: we describe how photoswitchable peptidomimetics modulate the activity of the MLLl enzyme affecting epigenetic states.
Funder
European Cooperation in Science and Technology
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC00137A
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