Hg/Pt-catalyzed conversion of bromo alkynamines/alkynols to saturated and unsaturated γ-butyrolactams/lactones via intramolecular electrophilic cyclization
Author:
Affiliation:
1. Medicinal & Process Chemistry Division
2. CSIR-Central Drug Research Institute
3. Lucknow 226031
4. India
5. Academy of Scientific and Innovative Research
Abstract
An intramolecular electrophilic cyclization of bromo-alkynols/alkynamines is achieved for γ-butyrolactams, α,β-unsaturated γ-butyrolactones/lactams, α-bromoketone and oxazinones under ambient conditions.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB02125A
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