NMR and MS urinary metabolic phenotyping in kidney diseases is fit-for-purpose in the presence of a protease inhibitor-Reference-Cited by-同舟云学术

NMR and MS urinary metabolic phenotyping in kidney diseases is fit-for-purpose in the presence of a protease inhibitor

Published:2019 Issue:1 Volume:15 Page:39-49
ISSN:2515-4184
Container-title:Molecular Omics
language:en
Short-container-title:Mol. Omics

Author:

Boulangé Claire L.¹²³^ORCID,Rood Ilse M.⁴⁵⁶⁷^ORCID,Posma Joram M.⁸⁹¹⁰¹¹²,Lindon John C.¹²³⁸⁹^ORCID,Holmes Elaine¹²³⁸⁹,Wetzels Jack F. M.⁴⁵⁶⁷,Deegens Jeroen K. J.⁴⁵⁶⁷,Kaluarachchi Manuja R.¹²³^ORCID

Affiliation:

1. Metabometrix Ltd

2. London SW7 2AZ

3. UK

4. Department of Nephrology

5. Radboud University Medical Center

6. Nijmegen

7. The Netherlands

8. Imperial College London

9. Division of Computational and Systems Medicine

10. Department of Surgery and Cancer

11. Faculty of Medicine

Abstract

When using an appropriate data analysis pipeline, protease inhibitor (PI)-containing urine samples are fit-for-purpose for metabolic phenotyping of patients with nephrotic syndrome and proteinuria.

Funder

Seventh Framework Programme

ZonMw

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Genetics,Molecular Biology,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MO/C8MO00190A

Reference43 articles.

1. Changing etiologies of unexplained adult nephrotic syndrome: A comparison of renal biopsy findings from 1976–1979 and 1995–1997