Electron-rich benzofulvenes as effective dipolarophiles in copper(<scp>i</scp>)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides-Reference-Cited by-同舟云学术

Electron-rich benzofulvenes as effective dipolarophiles in copper(i)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides

Published:2023 Issue:20 Volume:14 Page:5460-5469
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Chang Xin¹²,Liu Xue-Tao¹²,Li Fangfang³,Yang Yuhong³,Chung Lung Wa³^ORCID,Wang Chun-Jiang¹²^ORCID

Affiliation:

1. Engineering Research Center of Organosilicon Compounds & Materials, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China

2. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Shanghai, 230021, China

3. Department of Chemistry and Guangdong Provincial Key Laboratory of Catalysis, Southern University of Science and Technology, Shenzhen, 518055, China

Abstract

Electron-rich benzofulvenes serve as 2π-components in Cu-catalyzed asymmetric 1,3-DC reactions of azomethine ylides, affording chiral spiro-pyrrolidines in high yields with exclusive chemo-/regioselectivity and moderate to excellent stereoselectivity.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Hubei Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC00435J

Reference115 articles.