Total synthesis of a thromboxane receptor antagonist, terutroban
Author:
Affiliation:
1. Division of Natural Products Chemistry
2. CSIR-Indian Institute of Chemical Technology
3. Hyderabad
4. India 500 007
5. Academy of Scientific and Innovative Research
Abstract
Synthesis of terutroban (2) is achieved following a non-Diels–Alder approach using cost-effective chemicals.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/OB/C4OB02302A
Reference43 articles.
1. Terutroban sodium
2. Ramatroban (BAY u 3405): A Novel Dual Antagonist of TXA2 Receptor and CRTh2, a Newly Identified Prostaglandin D2 Receptor
3. Asymmetric Chemoenzymatic Synthesis of Ramatroban Using Lipases and Oxidoreductases
4. Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists
5. Formal Synthesis of Antiplatelet Drug, Beraprost
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