Local release of siRNA using polyplex-loaded thermosensitive hydrogels-Reference-Cited by-同舟云学术

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Local release of siRNA using polyplex-loaded thermosensitive hydrogels

Published:2020 Issue:18 Volume:12 Page:10347-10360
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Fliervoet Lies A. L.¹²³⁴⁵,Zhang Heyang⁶⁷⁸⁹¹⁰,van Groesen Emma¹¹¹²¹³¹⁴¹⁵,Fortuin Kyra¹²³⁴⁵,Duin Naut J. C. B.¹²³⁴⁵,Remaut Katrien⁶⁷⁸⁹¹⁰,Schiffelers Raymond M.¹⁶¹⁷¹⁸¹⁹^ORCID,Hennink Wim E.¹²³⁴⁵^ORCID,Vermonden Tina¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmaceutics

2. Utrecht Institute for Pharmaceutical Sciences (UIPS)

3. Faculty of Science

4. Utrecht University

5. 3508 TB Utrecht

6. Laboratory of General Biochemistry and Physical Pharmacy

7. Faculty of Pharmaceutical Sciences

8. Ghent University

9. Ghent 9000

10. Belgium

11. Biological Chemistry Group

12. Institute of Biology Leiden

13. Leiden University

14. Sylvius Laboratories

15. 2333 BE Leiden

16. Department of Clinical Chemistry and Haematology

17. University Medical Center Utrecht

18. 3508 GA Utrecht

19. the Netherlands

Abstract

An injectable thermosensitive hydrogel to promote local and sustained release of small nanosized (10–20 nm) siRNA polyplexes.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/D0NR03147J

Reference53 articles.

1. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

2. Patisiran: First Global Approval

3. The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

4. RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

5. Silencing or Stimulation? siRNA Delivery and the Immune System

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3. Multifunctional siRNA/ferrocene/cyclodextrin nanoparticles for enhanced chemodynamic cancer therapy;Nanoscale;2024

4. siRNA delivery from cationic nanocarriers prepared by diffusion‐assisted loading in the presence and absence of electrostatic interactions;Journal of Applied Polymer Science;2023-12-15

5. Bioinspired Spatiotemporal Management toward RNA Therapies;ACS Nano;2023-12-13

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