Lighting up RNA-specific multi-photon and super-resolution imaging using a novel zinc complex

Author:

Feng Zhihui1,Zhang Dongxue12,Guo Hui3,Su Wenqing3,Tian Yupeng3ORCID,Tian Xiaohe1ORCID

Affiliation:

1. Huaxi MR Research Centre (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, Department of Radiology and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu 610000, Sichuan Province, China

2. Equipment and Material Department, West China Hospital, Sichuan University, Chengdu, China

3. College of Chemistry and Chemical Engineering, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Key Laboratory of Structure and Functional Regulation of Hybrid Materials (Anhui University) Ministry of Education, Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, P.R. China

Abstract

Terpyridine Zn(ii) complex has good AIE and three-photon absorption activity, and the ultra-bright fluorescence induced by the aggregation state of Zn complex can assist the multi-photon and super-resolution imaging of nuclear RNA.

Funder

National Natural Science Foundation of China

West China Hospital, Sichuan University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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