PtI2(DACH), the iodido analogue of oxaliplatin as a candidate for colorectal cancer treatment: chemical and biological features-Reference-Cited by-同舟云学术

PtI2(DACH), the iodido analogue of oxaliplatin as a candidate for colorectal cancer treatment: chemical and biological features

Published:2017 Issue:10 Volume:46 Page:3311-3317
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Cirri D.¹²³⁴⁵,Pillozzi S.⁶³⁷⁵,Gabbiani C.⁸⁹¹⁰⁵,Tricomi J.¹²³⁴⁵,Bartoli G.¹²³⁴⁵,Stefanini M.¹¹⁴⁵,Michelucci E.¹²³¹³⁵,Arcangeli A.¹²³⁴⁵,Messori L.¹²³⁴⁵,Marzo T.⁸⁹¹⁰⁵¹^ORCID

Affiliation:

1. Laboratory of Metals in Medicine (MetMed)

2. Department of Chemistry

3. University of Florence

4. Sesto Fiorentino

5. Italy

6. Department of Experimental and Clinical Medicine

7. 50134 Firenze

8. Department of Chemistry and Industrial Chemistry

9. University of Pisa

10. 56124 Pisa

11. DIVAL Toscana Srl

12. Mass Spectrometry Centre (CISM)

13. 50019 Sesto Fiorentino

Abstract

PtI₂(DACH) has been prepared and tested. PtI₂(DACH) shows different chemical and biological features than oxaliplatin, manifesting cellular effects nearly comparable to those of parent drug in three cellular lines of CRC.

Funder

European Cooperation in Science and Technology

Associazione Italiana per la Ricerca sul Cancro

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/DT/C6DT03867K

Reference21 articles.

1. Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors

2. The Staging of Colorectal Cancer: 2004 and Beyond