Kaempferide, the most active among the four flavonoids isolated and characterized from Chromolaena odorata, induces apoptosis in cervical cancer cells while being pharmacologically safe-Reference-Cited by-同舟云学术

Kaempferide, the most active among the four flavonoids isolated and characterized from Chromolaena odorata, induces apoptosis in cervical cancer cells while being pharmacologically safe

Published:2015 Issue:122 Volume:5 Page:100912-100922
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Nath Lekshmi R.¹²³⁴,Gorantla Jaggaiah N.⁵⁶⁷⁴,Joseph Sophia Margaret¹²³⁴,Antony Jayesh¹²³⁴,Thankachan Sanu¹²³⁴,Menon Darsan B.¹²³⁴,Sankar S.⁸⁹¹⁰⁴,Lankalapalli Ravi S.⁵⁶⁷⁴,Anto Ruby John¹²³⁴

Affiliation:

1. Division of Cancer Research

2. Rajiv Gandhi Centre for Biotechnology

3. Thiruvananthapuram-695014

4. India

5. Chemical Sciences and Technology Division

6. CSIR-National Institute for Interdisciplinary Science and Technology

7. Thiruvananthapuram-695019

8. Department of Pathology

9. Government Medical College

10. Thiruvananthapuram-695011

Abstract

We report the isolation and characterization of four compounds from a cytotoxic fraction F-17, isolated from the DCM extract of C. odorata by bioactivity guided fractionation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA19199H

Reference41 articles.

1. Worldwide burden of cervical cancer in 2008

2. Phenolic Compounds of Chromolaena odorata Protect Cultured Skin Cells from Oxidative Damage: Implication for Cutaneous Wound Healing.

3. Immunostimulatory effects of Uncaria perrottetii (A. Rich.) Merr. (Rubiaceae) vinebark aqueous extract in Balb/C mice

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