An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium
Author:
Affiliation:
1. Gut Health and Food Safety Research Programme
2. Institute of Food Research
3. Norwich
4. UK
5. Food and Health Research Programme
6. School of Medicine
7. Keio University
8. Tokyo 160-8582
9. Japan
10. Norwich Medical School
Abstract
Intestinal crypt fission is a homeostatic phenomenon, observable in healthy adult mucosa, but which also plays a pathological role as the main mode of growth of some intestinal polyps.
Funder
Royal Society
Biotechnology and Biological Sciences Research Council
Publisher
Oxford University Press (OUP)
Subject
Biochemistry,Biophysics
Link
http://pubs.rsc.org/en/content/articlepdf/2015/IB/C4IB00236A
Reference63 articles.
1. Morphological study of the regeneration mechanism of acetic acid-injured colon crypts in the rat
2. N. A. Wright and M. R.Alison, The biology of epithelial cell populations, Clarendon Press, Oxford, 1984, vol. 2
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