Antioxidative, membrane protective and antiapoptotic effects of melatonin, in silico study of physico-chemical profile and efficiency of nanoliposome delivery compared to betaine
Author:
Affiliation:
1. Institute of Biochemistry
2. Faculty of Medicine
3. University of Nis
4. 18000 Nis
5. Serbia
6. Department of Pharmacy
7. University of Maribor
8. Maribor 2000
9. Slovenia
Abstract
Hepatoprotective effects of melatonin mediated by the inhibition of apoptotic and oxidative processes and activation of survival pathways, in comparison with betaine, were studied in mouse hepatocytes undergone Fas-ligand apoptosis.
Funder
Ministry of Education, Science and Technological Development
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA24741E
Reference71 articles.
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2. Apoptosis: A Programme of Cell Death or Cell Disposal?
3. Fas and other cell death signaling pathways
4. Protective effect of interferon-? on the DNA- and RNA-degrading pathway in anti-Fas-antibody induced apoptosis
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