Synthesis and characterization of a biocompatible 13C1 isotopologue of trityl radical OX071 for in vivo EPR viscometry-Reference-Cited by-同舟云学术

Synthesis and characterization of a biocompatible ¹³C₁ isotopologue of trityl radical OX071 for in vivo EPR viscometry

Published:2022 Issue:24 Volume:147 Page:5643-5648
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Poncelet Martin¹²^ORCID,Ngendahimana Thacien³^ORCID,Gluth Teresa D.¹²^ORCID,Hoblitzell Emily H.²⁴,Eubank Timothy D.²⁴^ORCID,Eaton Gareth R.³^ORCID,Eaton Sandra S.³^ORCID,Driesschaert Benoit¹²⁵^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV, 26506, USA

2. In Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, 26506, USA

3. Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80210, USA

4. Department of Microbiology, Immunology, and Cell Biology, West Virginia University, School of Medicine, Morgantown, WV, 26506, USA

5. Eugene Bennett Department of Chemistry, West Virginia University, WV, 26506, USA

Abstract

We report an isotopologue of the trityl radical OX071, labeled with 13C at the central carbon highly sensitive to molecular tumbling.

Funder

National Cancer Institute

National Institute of Biomedical Imaging and Bioengineering

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D2AN01527G

Reference27 articles.

1. Phosphonated Trityl Probes for Concurrent in Vivo Tissue Oxygen and pH Monitoring Using Electron Paramagnetic Resonance-Based Techniques

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