Ultrasmall hybrid protein–copper sulfide nanoparticles for targeted photoacoustic imaging of orthotopic hepatocellular carcinoma with a high signal-to-noise ratio

Author:

Yan Huixiang12345ORCID,Chen Jingqin56789,Li Ying1011124,Bai Yuanyuan56789,Wu Yunzhu1234,Sheng Zonghai1378914,Song Liang56789ORCID,Liu Chengbo56789ORCID,Zhang Hai12341ORCID

Affiliation:

1. Department of Ultrasound

2. The Second Clinical College of Jinan University

3. Shenzhen People's Hospital

4. China

5. Research Laboratory for Biomedical Optics and Molecular Imaging

6. Shenzhen Key Laboratory for Molecular Imaging

7. Institute of Biomedical and Health Engineering

8. Shenzhen Institutes of Advanced Technology

9. Chinese Academy of Sciences

10. Division of Radiology

11. Department of Medicine

12. the University of Hong Kong Shenzhen Hospital

13. Paul C. Lauterbur Research Center for Biomedical Imaging

14. Shenzhen 518055

Abstract

A schematic illustration of CuS@BSA-RGD nanoparticle synthesis and the application of photoacoustic imaging in an orthotopic HCC model.

Funder

Shenzhen Science and Technology Innovation Commission

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangzhou Science, Technology and Innovation Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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