HepaChip-MP – a twenty-four chamber microplate for a continuously perfused liver coculture model

Author:

Busche Marius1234,Tomilova Olena1234,Schütte Julia1234,Werner Simon1234,Beer Meike1234,Groll Nicola1234,Hagmeyer Britta1234,Pawlak Michael1234,Jones Peter D.1234ORCID,Schmees Christian1234,Becker Holger564ORCID,Schnabel Juliane564,Gall Karsten784,Hemmler Roland784,Matz-Soja Madlen91011124,Damm Georg131415124,Beuck Simon16174,Klaassen Tobias16174,Moer Jana18194,Ullrich Anett18194,Runge Dieter18194,Schenke-Layland Katja123420,Gebhardt Rolf91011124,Stelzle Martin1234ORCID

Affiliation:

1. NMI Natural and Medical Sciences Institute

2. University of Tübingen

3. Reutlingen

4. Germany

5. Microfluidic ChipShop GmbH

6. Jena

7. Ionovation GmbH

8. Bissendorf

9. Section of Hepatology

10. Clinic and Polyclinic for Gastroenterology, Hepatology, Infectiology, Pneumology

11. University Clinic Leipzig

12. Leipzig

13. Department of Hepatobiliary Surgery and Visceral Transplantation

14. University Hospital

15. Leipzig University

16. A & M Labor fuer Analytik und Metabolismusforschung Service GmbH

17. Bergheim

18. PRIMACYT Cell Culture Technology GmbH

19. Schwerin

20. Department of Women's Health

Abstract

HepaChip-MP: a 24-culture-chamber, automated microfluidic in vitro model of the liver sinusoid in multiwellplate format.

Funder

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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