Novel small molecular dye-loaded lipid nanoparticles with efficient near-infrared-II absorption for photoacoustic imaging and photothermal therapy of hepatocellular carcinoma

Author:

Chen Qingshan12345,Chen Jingqin678910,He Mu12345,Bai Yuanyuan678910,Yan Huixiang1112131415ORCID,Zeng Ning12345,Liu Fangyan678910,Wen Sai12345,Song Liang678910ORCID,Sheng Zonghai16891017,Liu Chengbo678910ORCID,Fang Chihua12345ORCID

Affiliation:

1. Department of Hepatobiliary Surgery

2. Zhujiang Hospital

3. Southern Medical University

4. Guangzhou

5. PR China

6. Research Laboratory for Biomedical Optics and Molecular Imaging

7. Shenzhen Key Laboratory for Molecular Imaging

8. Institute of Biomedical and Health Engineering

9. Shenzhen Institutes of Advanced Technology

10. Chinese Academy of Sciences

11. Department of Ultrasonography

12. The Eighth Affiliated Hospital

13. SUN YAT-SEN University

14. Shenzhen

15. China

16. Paul C. Lauterbur Research Center for Biomedical Imaging

17. Shenzhen 518055

Abstract

The NIR-II PA and PTT nanoparticle based on the IR-1061 dye would benefit early diagnosis and treatment of HCC.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Guangdong Science and Technology Department

Guangzhou Municipal Science and Technology Project

Natural Science Foundation of Guangdong Province

Shenzhen Science and Technology Innovation Commission

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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