The use of pH-sensitive functional selenium nanoparticles shows enhanced in vivo VEGF-siRNA silencing and fluorescence imaging-Reference-Cited by-同舟云学术

The use of pH-sensitive functional selenium nanoparticles shows enhanced in vivo VEGF-siRNA silencing and fluorescence imaging

Published:2014 Issue:15 Volume:6 Page:9279-9292
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Yu Qianqian¹²³,Liu Yanan¹²³⁴⁵,Cao Chengwen¹²³,Le Fangling¹²³,Qin Xiuying¹²³,Sun Dongdong¹²³,Liu Jie¹²³

Affiliation:

1. Department of Chemistry

2. Jinan University

3. Guangzhou 510632, China

4. Department ABCT

5. The Hong Kong Polytechnic University

Abstract

The pH-sensitive delivery system G2/PAH-Cit/SeNPs@siRNA enhances anti-tumor effects through VEGF gene silencing and reduces angiogenesis, with no side effects in organs.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2014/NR/C4NR02423K

Reference43 articles.

1. In Vitro and In Vivo gene delivery mediated by Lactosylated Dendrimer/α-Cyclodextrin Conjugates (G2) into Hepatocytes

2. Polymeric Materials for Gene Delivery and DNA Vaccination

3. Knocking down barriers: advances in siRNA delivery

4. siRNA delivery systems for cancer treatment

5. Interfering with disease: a progress report on siRNA-based therapeutics

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