Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia-Reference-Cited by-同舟云学术

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Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia

Published:2017 Issue:8 Volume:9 Page:1106-1119
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Xu Jingshu¹²³⁴⁵^ORCID,Church Stephanie J.⁶⁷⁸⁹¹⁰^ORCID,Patassini Stefano¹²³⁴⁵^ORCID,Begley Paul⁶⁷⁸⁹¹⁰^ORCID,Waldvogel Henry J.¹¹¹²³¹³⁵^ORCID,Curtis Maurice A.¹¹¹²³¹³⁵^ORCID,Faull Richard L. M.¹¹¹²³¹³⁵^ORCID,Unwin Richard D.⁶⁷⁸⁹¹⁰^ORCID,Cooper Garth J. S.¹²³⁴⁵^ORCID

Affiliation:

1. School of Biological Sciences

2. Faculty of Science, and the Maurice Wilkins Centre for Molecular Biodiscovery

3. University of Auckland

4. Auckland 1142

5. New Zealand

6. Centre for Advanced Discovery and Experimental Therapeutics

7. Central Manchester University Hospitals NHS Foundation Trust (CMFT)

8. Manchester M13 9WL

9. UK

10. Division of Cardiovascular Sciences

11. Centre for Brain Research

12. Faculty of Medical and Health Sciences

13. Auckland

Abstract

Widespread brain-copper deficiency in patients with Alzheimer's dementia (red) compared to controls (blue).

Funder

University of Auckland

Neurological Foundation of New Zealand

Maurice and Phyllis Paykel Trust

Tertiary Education Commission

Health Research Council of New Zealand

Ministry of Business, Innovation and Employment

Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MT/C7MT00074J

Reference96 articles.

1. Global prevalence of dementia: a Delphi consensus study

2. The global prevalence of dementia: A systematic review and metaanalysis

3. Alzheimer's disease: strategies for disease modification

4. Alzheimer’s Disease

5. Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

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