Discovery of potent nucleotide pyrophosphatase/phosphodiesterase3 (NPP3) inhibitors with ancillary carbonic anhydrase inhibition for cancer (immuno)therapy-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Discovery of potent nucleotide pyrophosphatase/phosphodiesterase3 (NPP3) inhibitors with ancillary carbonic anhydrase inhibition for cancer (immuno)therapy

Published:2021 Issue:7 Volume:12 Page:1187-1206
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Lee Sang-Yong¹²³⁴⁵^ORCID,Namasivayam Vigneshwaran¹²³⁴⁵^ORCID,Boshta Nader M.¹²³⁴⁵^ORCID,Perotti Arianna¹²³⁴⁵,Mirza Salahuddin¹²³⁴⁵^ORCID,Bua Silvia⁶⁷⁸⁹¹⁰^ORCID,Supuran Claudiu T.⁶⁷⁸⁹¹⁰^ORCID,Müller Christa E.¹²³⁴⁵^ORCID

Affiliation:

1. PharmaCenter Bonn

2. Pharmaceutical Institute

3. Department of Pharmaceutical & Medicinal Chemistry

4. University of Bonn

5. D-53121 Bonn

6. Dipartimento Neurofarba

7. Sezione di Scienze Farmaceutiche e Nutraceutiche

8. Università degli Studi di Firenze

9. Florence

10. Italy

Abstract

The first potent NPP3 inhibitors were discovered, which were found to additionally block cancer-related carbonic anhydrases.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/MD/D1MD00117E

Reference64 articles.

1. Cellular function and molecular structure of ecto-nucleotidases

2. NPP-type ectophosphodiesterases: unity in diversity

3. Nucleotide Pyrophosphatases/Phosphodiesterases on the Move

4. A 3D view of autotaxin

5. Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis and in vitro evaluation of novel sulfonylurea and sulfonylthiourea as ectonucleotidases inhibitors;Results in Chemistry;2024-01

2. Design and synthesis of new adamantyl derivatives as promising antiproliferative agents;European Journal of Medicinal Chemistry;2023-01

3. Cancer Therapeutic Targeting of Hypoxia Induced Carbonic Anhydrase IX: From Bench to Bedside;Cancers;2022-07-06

4. ATP and Adenosine Metabolism in Cancer: Exploitation for Therapeutic Gain;Pharmacological Reviews;2022-07

5. Nucleotide pyrophosphatase/phosphodiesterases (NPPs) including NPP1 and NPP2/ ATX as important drug targets: A patent review (2015-2020);Expert Opinion on Therapeutic Patents;2022-04-12

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3